Download Drug Design by E. J. Ariëns (Eds.) PDF

By E. J. Ariëns (Eds.)

Show description

Read or Download Drug Design PDF

Best industrial & technical books

Suspension acoustics

This e-book is an creation to the physics of suspensions of bubbles, droplets, and good debris in either gases and fluids. instead of treating every one blend individually, a unified process is used that allows so much particle-fluid blend varieties to be mentioned jointly. to do that, the booklet first offers an in depth dialogue of the elemental particle motions that small debris can maintain, paying specific realization to translations and pulsations, and to the thermal results that take place due to these motions.

Industrielle Feuchtemessung: Grundlagen, Messmethoden, technische Anwendungen

Content material: bankruptcy 1 Wasser - Baustein der Entwicklung (pages 1–9): bankruptcy 2 Begriffe, Definitionen zur Thermodynamik (pages 11–56): bankruptcy three Wasser in festen, gasförmigen und flüssigen Stoffen (pages 57–65): bankruptcy four Messverfahren zur Erfassung der Feuchte in gasförmigen, festen und flüssigen Medien (pages 67–176): bankruptcy five Methodik zur Auswahl der Messverfahren und Gerätetechnik bei der Materialfeuchtemessung (pages 177–194): bankruptcy 6 Begriffe zur Zuverlässigkeit und Überprüfbarkeit von Feuchtemesstechnik (pages 195–201): bankruptcy 7 Feuchtemessung in der Umwelt, Meteorologie und Landwirtschaft (pages 203–248): bankruptcy eight Applikationen zur Nahrungs- und Genussmittelindustrie (pages 249–299): bankruptcy nine Feuchtemessung in Industrieanlagen (pages 301–354): bankruptcy 10 Applikationen in der Chemie, Pharmazie und Kunststoffindustrie (pages 355–392): bankruptcy eleven Applikationen bei der Herstellung und Verarbeitung von Papier und Textilien (pages 393–418): bankruptcy 12 Feuchtemessung in der Bauindustrie (pages 419–446): bankruptcy thirteen Feuchtemessung unter Laborbedingungen (pages 447–483): bankruptcy 14 Einsatz von Feuchtemesstechnik in der Raumfahrtindustrie (pages 485–517):

Hydrofunctionalization

Valentine P. Ananikov, Irina P. Beletskaya: Alkyne and alkene insertion into metal-heteroatom and metal-hydrogen bonds – the main phases of hydrofunctionalization procedure. - Akihiko Ishii* and Norio Nakata: The Mechanism for Transition Metal-Catalyzed Hydrochalcogenation of Unsaturated natural Molecules.

Photochemistry and photophysics : concepts, research, applications

This textbook covers the spectrum from easy recommendations of photochemistry and photophysics to chose examples of present functions and learn. basically established, the 1st a part of the textual content discusses the formation, homes and reactivity of excited states of inorganic and natural molecules and supramolecular species, in addition to experimental concepts.

Additional resources for Drug Design

Example text

It is resistant to metals and metal-complexing substances; the preferred electron donor is NADH (344). 3. Reactions Involving Hydrogen a. Introduction. In reactions involving hydrogen a transfer of hydrogen may be catalyzed from a substrate to an acceptor (cosubstrate) or vice versa. Often this type of oxidation-reduction reaction is found to be reversible. Three types of conversions involving hydrogen will be illustrated with a few examples. These reactions are dehydrogenation of hydroxyl to carbonyl, dehydrogenation of aldehyde to carboxyl, and the formation of a double bond.

Monooxygenases. i. Introduction. In this group are found those enzymes that catalyze the incorporation of one of the two atoms of atmospheric oxygen into the substrate. The other atom is reduced to water with the help of an electron donor. Because of the hybrid character of the monooxygenation Mason proposed the name: "mixed function oxygénation" (277). Studies with cell-free preparations of monooxygenases have led to an understanding of the diverse nature of the electron donor and cofactor requirements.

1. · This would be a good method to prepare special semisynthetic penicillins in order to test their antibiotic properties (131, 421). 2. Halogen Peroxidase An enzyme system derived from Caldariomyces fumago is capable of carrying out halogenations in vitro in the presence of a potassium halide and hydrogen peroxide. Halogenation of the 17a-position occurs with 16-ketoprogesterone and of the 16-position with 15-keto-l-dehydrotestololactone (304). The compound 9(1 l)-dehydroprogesterone is converted into 9a-Br-llß- 24 R.

Download PDF sample

Rated 4.83 of 5 – based on 44 votes