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By Newton D. E.

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Sample text

Quinine was, for centuries, the most important drug available for the treatment of malaria, a disease that affects hundreds of millions of people around the world. As a result of Woodward’s work, it became possible to manufacture the drug synthetically rather than to collect it from its natural source, chinchona bark. Robert Woodward was born in Boston on April 10, 1917. He graduated from Quincy High School, in Quincy, Massachusetts, in 1933, at the age of traditional herbal remedies, including qing hoa.

Openings develop in the cell membrane, water enters, and the cell bursts and dies. More than 150 different antibiotics are now available for treating a host of infectious diseases that had once been considered incurable, diseases such as plague, pneumonia, tuberculosis, typhus, typhoid fever, scarlet fever, staphylococcus infections, gonorrhea, meningitis, pertussis (whooping cough), and urinary tract infections. These antibiotics 30 CHEMISTRY OF DRUGS exist because researchers came to understand how certain microorganisms live and grow.

The use of natural products as drugs among some people remains as popular today as it has for centuries in spite of considerable uncertainty as to the efficacy and, in some cases, the safety of such chemicals. Researchers continue to explore the mechanisms by which such chemicals work, their effectiveness in combating certain diseases, and the possibilities of developing analogs that may be both more effective and safer for use in treating human diseases. 46 CHEMISTRY OF DRUGS CURRENT INFORMATION ON CERTAIN DIETARY SUPPLEMENTS ➢ DIETARY SUPPLEMENT CURRENT INFORMATION Black cohosh Preliminary evidence for effective use against “hot flashes” and other menstrual problems Coenzyme Q10 Stimulates immune system; protects against certain heart disorders Garlic products No reduction in risk for breast, lung, gastric, colon, or rectal cancer when used for less than three to five years; no evidence on protection from heart disease; some evidence for limited protection against laryngeal, gastric, colorectal, and endometrial cancers Green tea Early, limited, and contradictory studies suggest some protection against certain types of cancer Milk thistle Ambiguous and uncertain evidence for protection against liver disorders St.

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